Nanofiber Platforms Advancing Photodynamic Therapy, February 14, 2025

Our review article titled “Electrospun Nanofiber Platforms for Photodynamic Therapy: Role and Efficacy in Cancer, Antimicrobial, and Wound Healing Applications” has been published in Macromolecular Materials & Engineering.

This review highlights how electrospun nanofibrous scaffolds provide a powerful platform for photodynamic therapy (PDT) by enabling efficient photosensitizer delivery, controlled release, and targeted reactive oxygen species (ROS) generation. Through light activation, these systems achieve selective cytotoxicity, effectively targeting cancer cells and pathogens while minimizing damage to healthy tissue.

Beyond cancer therapy, photosensitizer-loaded nanofibers show strong potential in wound healing, supporting cell proliferation, tissue regeneration, and microbial inhibition. The article summarizes recent advances and future perspectives, paving the way for next-generation strategies in cancer treatment, infection control, and regenerative medicine.